Direct to Consumer Advertising of Prescription drugs

purport to Con substanceer ad of prescription do drugs medicament drugsAbstract In pharmaceutic industry, promotional advertises ar almostly targeted towards atomic number 101s but in young geezerhood manner has shifted towards consumer advertisement. In m whatsoever cases of target to Consumer Advertisement (DTCA) the pharmaceutical marketers and manufactures creates wad among forbearings towards distemper and ultimately towards filth. It provokes the longanimouss to try additive learning on the brand and push for its prescription drug genesis. Objective of this demand is to determine strength of the physicians towards DTCA, and what uttermost uncomplainings request for get aroundicular brand leads to true prescription coevals of the publicise drugs. This reading reveals that the heals universally have substantiative locating towards DTCA and be pull up stakes to en combine pertinent training to the patients and in some cases eve provide sa mple of medicines or go for immediately prescribing, if lay out relevant, as accepted by the patient. This study justifies the pharmaceutical industry manufacturers using up in DTCA. It is too thought provoking for wellness insurance getrs that prescription drugs atomic number 18 being publicize this instant which may lead to increased practice of medicine cost and ill-use of medicine.Key words Direct to consumer advertising, Direct to Consumer Advertised blemish, Over the heel counter drugs, ethical drug drug. Physicians locating.I INTRODUCTIONCompanies rely heavily on carrefour elaborate to physicians, which be the customer, (Zangla, 2004). To increase boilersuit sales figures marketers started advertising directly to consumers of disease and even drug brands, (Amaldoss He, 2009). DTCA is not allowed specially for prescription drugs, (Donohue Berndt, 2010). sensation line of credit is that DTCA is a public service message just virtually a particular di sease and neverthe slight plays a role as selective discipline provider and motivates pot to seek proper discourse if required (Kuhn, 2006). many researchers appoint DTCA comfortably for General public health, (Bradford, Kleit, Nietert, Ornstein, 2005) and beneficial for patient lot (Murray, Lo, pollock, D wholenesslan, Lee, 2004). So it is con spatial relationred as DTCA has twain merits and demerits, (Murray, 2003)1.1 Research ObjectiveIn recent years pharmaceutical Companies drastically increased their spending on Direct to Consumer Advertising (DTCA) (Herzenstein, Misra Posavac, 2005). In 1997 Federal drug authority (FDA) permitted DTCA and subsequently pharmaceutical companies started increasing their expenditure on direct advertisement to provoke consumers to train their desexualizes slightly the drug (Green, 2007). Patient is to a greater extent comfortable in exploitation drug brand which is familiar to patient, (Zuvekas, 2008). Consumers have collateral mental attitude towards DTCA and tries to fix out additional reading about Directly to Consumer Advertised Brand (DTCAB). To get additional reading patient natters their doctor, (Herzenstein, Misra, Posavac, 2005).Asking movements by patients has bullnecked influence on doctors selection criteria of drugs (Iizuka Jin 2005). General attitude of physicians towards DTCA its impact on prescription generation is still unk flatn (Herzenstein, et al., 2005).If physicians have positive general attitude towards DTCA, it may lead to veritable prescription generation. muchover if patients shows to a greater extent(prenominal) likelihood of searching additional information tries to inquire additional information by inquire questions from physician about DTCAB as well as leads to prescription generation (Herzenstein, et al., 2005). Information inquired from the physician about DTCAB of medicine is taken as punt commutative unsettled, pressurizes physicians towards prescribing t hat specific brand of drugs. Patients adherence influenced by DTCA motivates patients to seek additional information about the drug from physicians (Amaldoss Chuan, 2009).1.2 Rationale of study1.2.1 Increased spending on DTCA from pharmaceutical companies. pharmaceutical companies have increased their spending in last decade, and they are planning to do much (Atherly Rubin, Feb 2008). Physicians are con postred to be the best judge to decide medicine , keeping in make the patients and drugs characteristics. Due to information flow and door with electronic and chump media, consumer tries to get more information about the drug and disease. With this the pharmaceutical companies started promoting prescription drugs directly to consumers. At the end of many advertisements it is advised to consult your doctor for only information, but ultimate goal is the prescription generation. These advertisements provokes patients to consult their physicians and request information and if it is appropriate consequently whether it can be apply or not. It is presumed by the companies that doctor will prescribe the medicine as per patient request, but it is still unknown that what is the general attitude of doctors towards direct to consumer advertisement This study will help marketers of pharmaceutical companies in descrying the assist to the question, whether they are helping people in getting medication, from physicians perspective, and are they rightfully making returns on this investment on DTCA.1.2.2 Health policy makers.Drugs are classified in cardinal categories, one is Over the Counter Drugs (OTC) and an new(prenominal)(prenominal) is called Prescription drugs (PD). OTC drugs are usual drugs which have comparatively lesser side effects and can be used without cite of physicians. conversely the PD which are of either critical use or may be associated with serious side effects, and can only be used if advised by physicians. In like manner promotion of P D were made only to the physicians through detailing. Pertaining to the severity of life and death think to use of PD, DTCA should not be done for PD. But PD are being denote under the head of Disease Advertising (DA). It should be the major concern for health policy maker either the PD are being used appropriately as per physicians advice or not. As extensive DTCA of PD may lead to subvert of medicine, increased intercession cost and unnecessary visits to physicians. DTCA should not have that much impact to vex prescription of DTCAB, if it is thusly specific policies should be developed to balance the use of DTCA with its risks.1.2.3 Knowledge contribution.It has already been explored in many researches that DTCA has both merits and demerits. Some physicians largely perceive that DTCA is good for patient overall health but from former(a) school of thought it is just in favor of pharmaceutical companies, only physicians can purify decide which drug to be used or not. In medical checkup exam sciences the selection of medicine is based on in the of import three brokers, kind of disease, doctors judgment, patients affordability and liking or psychological experience factor of any brand (Prosser, Almond and Walley, 2003). In previous researches the impact of both physicians and consumers have been explored. But the combined impact of both unsettleds has not been canvas before. This study for the first time explores the combined effect of the two main self-sustaining covariants. My research will find out the preference of physicians towards DTCA and whether information seeking by the patients leads to prescription generation.II LITERATURE REVIEWPharmaceutical industry is heavily driven by customers (doctors) and really marketing and exchange intensive (Scherer, 1990). Primarily the focus was only on doctors (customers) but late the trend is also shifting towards addressing consumers directly (Matthews, 2001). The medium used for accessing co nsumers is electronic media including the internet and television advertisements, consumers are now able to freely access information about drugs and their brands which in some cases can lead to upon of medicine and increased cost of treatment (Matthews et al., 2001). Pharmaceutical companies are now targeting advertisements towards patients which entice patients to ask for prescription of only advertised drug, the patients behavior is also effecting and directing the health systems. Matthews (2001) quoted Dr. Reardon, ex president of American Medical familiarity (AMA), has insightfully noted,Patients themselves are also creating a strong impetus for change. Disillusioned by restrictions on coverage and care, they are increasingly demanding pickaxe of physician, hospital, and even sign of health plan. More than ever, patients see physicians as the essential point of trust in a changing system, and demand choice and stability in their vital relationships with their doctors. At th e same time, patients themselves are becoming crack educated, not only about insurance options but also about medical treatments. Today, thanks to the Internet, trends in product advertising, and the massive proliferation of medical information, patients are break in equipped to take part in their care than ever before. sort of than simplifying the physicians job, however, this increased patient knowledge base is creating new challenges.The different argument that supports DTCA says that it encourages hard to reach sections of populations to seek information about diseases, but it should be balanced against the increased cost of medicine from unnecessary requests generated by DTCA (Murray Pollack Donelan and Lee, 2003). DTCA has both positive and prejudicious effects on health behaviors, health service utilization (Murray et, al., 2003). Almost five years back ads for prescription drugs were very rare but these are becoming very ordinary in recent years, and are being adver tised like any consumer goods, direct to consumer advertising (DTCA) has grown rapidly (Scherer, 2004). On the other side consumers behavior is supportive towards DTCA and would like to get more information and ask for a particular brand from physicians (Herzenstein, 2004). Another research shows that DTCA had no statistically noteworthy effect on the choice of antidepressant (Donohue Berndt, 2004). There are three variables involved in prescription choice, one is Patient characteristic, randomness is features of medication and third is physicians preference for medication choice, moreover detailing is launch to be the most effective in physicians preference for medication choice (Donohue Berndt, 2004). Increase in pharmaceutical pricing is due to increase in expenditure incurred on DTCA.2.1 Conceptual framework none the question arises that whether on that point is an impact of DTCA on sales or not (Scherer, 2004). It is also found that DTCA encourage patients to visit physi cians and use specific brand medicine (Iizuka, 2005). It is concord that DTCA has decreased the time in the midst of diagnosis and use of medicine and promotes the patients to consult their physician.2.1.1 Inquiry about additional information or request for prescription.It has been argued that patient may demand the product just because of the attractiveness and persuasion of the advertisement, rather than look in to the specialty of the drug and go for proper consultation from doctor (Bradford, 2005). This is not unusual in pharmaceutical, as is a operative change from the traditional emphasis on physicians detailing, it has been found that the traditional selling of pharmaceutical brands to physicians is changing and prescription drugs is being marketed directly to consumers, as other consumer goods, as detailing and price are found to be antonymous strategies for the firms in addition to the traditional detailing, (Brekkea, 2006)2.1.1 Actual prescription generation.Still questions arises about the impact of DTCA on welfare of patients, if allowed then will lead to More visits to physicians, and they pressurizes to get prescription of desired medicine. (Brekkea et al., 2006). It is also shown that the pharmaceutical manufacturers are also facing challenges from DTCA because they has to do extensive detailing to physicians because of DTCA is also being done, so it should be banned as to keep focus on detailing (Brekkea et al., 2006). It will induce demand for new users of antidepressant medicines and can mislead the usage if already that medicine is being used, and will lead to misuse of brand (Chad Meyerhoefer, 2007). Direct to consumer advertising is very important and of course polemic part, advertising in journals, detailing and distribution of samples are used along with direct to consumer advertising which may leads to induce demand and generate more sales (Pasdirtz, 2009)III RESEARCH METHODOLOGYResearch ruleology is a system or methods fo llowed by particular discipline of an inquiry or investigation into a subject in order to discover or revise facts, theories, applications etc. (Oxford Dictionary, 2007). This study is an applied form of research confidential information to the basic knowledge contribution, and is an extension of work done by Zachry, (2003). As pharmaceutical industry is very important, it has to play an important role, on one side it claims to be for better health of patients but no question they are making huge profits, here comes the role of health policy makers to make it justified. Moreover it is to find out the general attitude of physicians about DTCA and information asked by patients about any particular DTCAB, and its relation with substantial prescription generation if asked by patient.3.1 Problem Statement HypothesisPharmaceutical companies in Pakistan are promoting their brands directly to consumers (patients), now the question isWhat is the attitude of physicians towards DTCA, and do they provide relevant information and prescribe medicine if asked by patient. positivistic attitude of physicians and information asked by patients of advertised medicine leads to prescription generation Now the objective of study is qualitative estimation of attitude, and what physicians are most likely to do if patient inquires information after exposure of pharmaceutical advertisement. Even patient may ask for prescription of specific drug, then what is the usual response of physician.3.2 HypothesisH-1 Attitude of physicians towards Direct to consumer advertisement is positive.H-2 Physicians provides information of drug which is asked by patient after exposure to pharmaceutical advertisement.H-3 If found relevant, physicians prescribe the particular drug which is requested by patient on exposure to pharmaceutical advertisement.H-4 Positive attitude of physicians towards DTCA and query about information of a particular brand of medicine leads to actual prescription generatio n.ATTITUDE3.3 mannikinIndependent protean 1PRESCRIPTION GENERATIONAttitude of Physicians towards Direct to Consumer Advertising of prescription drugsDependent VariableActual Prescription multiplication on request from patient of DTCAB medicineINFORMATIONReaction on request of information about particular DTCAB medicineIndependent Variable 2PRESCRIPTION GENERATIONDependent VariableActual Prescription Generation on request from patient of DTCAB medicine 3.4 Data armyData was collected in field setting, respondent were general practicing Doctors/Physicians in hospital setting, as per previously done by (Friedman, 2006) to know the attitude of doctors. We selected hospitals because it has been found that hospitals play an important role in direct to consumer advertising (Adeoye Bozic, 2007),.3.5 Sample and Populationwe choose leading hospitals of Rawalpindi/ Islamabad which have elevated patient turnover, i.e Pakistan institute of medical Sciences, Rawalpindi general hospital , Nescom Hospital and Shifa International. Within these hospitals we selected doctors on judgmental basis, as doctor who is dealing with more than 50 get in patients as previously done by (Taneja, Arora and Kaushik, 2007) and found appropriate. Sample sizing was taken 250, as per sample size taken by other researchers for the same kind of purpose (Bhanji, Baron, Benjamin, Lacy, Gross, Goin, Summner, Fischer, and Slaby 2008).3.6 InstrumentationA questionnaire was adopted from two authors. Questionnaire has three parts, in first part general attitude of physicians towards direct to consumer advertising (Donhue Berndt, 2004), and in second part the likelihood behavior of physician if patient asks for more information related to drug being advertised directly, and in last part the likelihood of physician if patient asks for prescription of certain medicine (Zachry,Dalen, and Jackson, 2003).3.7 Data abbreviationThese two were unaffiliated variable and one variable of prescription g eneration is dependant variable. Quantitative method were used, Microsoft Excel and SPSS was used to calculate percentages and relative comparison in questions through as per previous research done by Bhanji, 2008.IV determination AND ANALYSIS4.1 Data Reliability and NormalityCollected data is formalize from Cronbachs-Alpha lever which is used by many researchers like Zachry Dalen, and Jackson, (2001,2003). The value came up to 0.8 which is acceptable as it should beis more than 0.6. Taneja, Arora and Kaushik, (2007) used descriptive statistical data analysis, I moreover used SPSS to regress two independent variable with dependent variable.4.2 Descriptive Statistics of Respondents4.2.1 Independent variable 1, attitude.In first part of questionnaire it is found that 40 % agree and 20 % strongly agree that it makes patients better informed and 46% agree with 32% strongly agree that it causes them to seek medical doctor. 40% agree that it also informs about side effects, altho ugh the data shows that in that respect is increase in medication cost. Little agreement on suggesting medicine from patients. More that half percent of people suggested that it is good trend in health care, and causes more time spent in straw man of doctor epoch handleing disease. 42% agree that this also helps in increases need towards treatment. 39% think that it not only provokes patients to visit doctor for better health but also encourages, 41%, patients to talk to their doctor about right concern. 41% agree that it also helps in following treatment instructions and 58% with 7% strongly agree that it improves the understanding of medical conditions and treatment.1 is for strong agreement, 2 is for agreement, 3 is neutral and 4 is for disagreement while 5 is strongly disagreement.General description and frequency analysis is given in display board 4.1OVERALL ATTITUDE OF PHYSICIANS TOWARDS DIRECT TO CONSUMER ADVERTISING ATTITUDEQuestions Asked formStd DeviationMake patient s better informed about their medical problems1.181.08 impel patients to seek medical care1.211.1Provide enough information on other treatments1.411.18Do a good job of informing patients of side effects1.31.15Have less or no impact on increase in medication cost1.081.03Helps doctors in suggesting medicines from patients1.061.02Are a positive trend in health care0.940.97Increase in time spent with doctor11.01Increases motivation towards treatment, overall drug consumption0.80.89Increase more doctor visit for better health1.471.21Encourages patients to talk to their doctor about their right concerns11Encourages people to follow treatment instructions or advice from their doctors1.151.07Helps patients get treatments they would not other get1.161.07Have less of no impact on driveing up the cost of prescription drugs1.171.08Improves peoples understanding of medical conditions and treatments0.890.944.2.2 Independent variable 2, information.44% agree that they generate frustrated, 37% get riled but 52% agree and 32% strongly agree that they answer patient question about medication if asked. Only 35% agree that they provide more information. General description and frequency analysis is given in Table 4.2LIKELLIHOOD OF PHYSICIANS WHEN ASKED FOR SPECIFIC defect DUE TO DTCA INFORMATIONQuestions askedVarianceStd. DeviationYou become frustrated with patient for asking for more information about disease or medicine1.571.25You become besotted with patient for asking for more information about disease or medicine1.421.19Answer patient questions about the medication0.790.89Provide more information to patient beyond original inquiry1.391.18 commence to change subject rather than discuss the medication1.41.18Explains that the information is probably beyond patients comprehension1.421.194.2.3 Dependent variable, actual prescription generation.It is revealed from data that 37% get frustrated, 36% get annoyed if asked to prescribe certain brand and 36% feel uncomfortable w ith this request, and even less willing to communicate to the patient 33%, mostly 41% are neutral. With this if samples are purchasable then 61% agree and 17% strongly agree to provide samples on patient request, it is also back up by agreement of 51% and strong agreement 24% that they will prescribe medicine if no medicine is available. But if found relevant, as while asking question of simply prescribing the medicine if is anyway relevant , to satisfy the patient then the agreement was 47% and only 8% with strong agreement. General description and frequency analysis is given in Table 4.3LIKELIHOOD OF PHYSICIANS ON REQUEST OF PATIENT FOR SPECIFIC BRAND PRESCRIPTION GENERATIONDependent VariableQuestions AskedVarianceStd. Deviation compel frustrated with patient for asking to try the medication1.131.06Become annoyed with patient for asking to try the medication0.960.98Feel uncomfortable with the medication request1.341.16Communicate to the patient your discomfort with the medicatio n request0.870.93Attempt to prescribe different medication to keep from promoting patient to ask for medication, if available0.930.96Provides samples of the medication, if available0.730.86Provide prescription of the medication if no samples available1.21.09 patently prescribes the medicine if is anyway relevant, to satisfy the patient1.111.064.3 Correlation Regression AnalysisSPSS was used to show the relationship between two independent variables i.e attitude of doctors towards DTCA and behavior likelihood if information asked by the patient and its impact on dependent variable which is actual prescription generation if requested by the patient.4.3.1 Model summary and analysis of variance.R value shows 40% relationship between dependent variable and independent variables. R straightforward shows 16.6% of the variant in dependent variable can be predicted by the combination of two independent variable. Durbin Watson value is 2.08 showing that there is very less multicollinearit y.analysis of variance statistics shows overall model significance, f value is 15.09, and sig value is less than 0.00 which is less than 0.05, and is the indicator of significance, so that we can go for retroversion analysis of independent variables on dependent variables. Durbin Watson value should be between 1.5 to 2.5 means that there is no or less multicollinearity, here the value is 2.08, it shows less chances of multicollinearity.4.4 If two independent variables combined collectively, Information + AttitudeData results with individual variables shows very weak relationship. with model significance. So It is dispenseed combined effect of both independent variables on dependent variables.4.4.1 Model summary and ANOVA.Model Summary shows overall model significance, which is less than 0.05, showing overall model fit, R value shows 78% dependence of dependent variable on independent variable. R square value is 0.61 showing magnitude of relationship between independent variable with dependent variable. 1% change in independent variable with 61 % change in dependent variable. Adjusted R square is the pure magnitude of relationship which is always less than the R square, 0.60. F Change statistics is 239.45 which is more than 1 then we can go for coefficients.ANOVA shows overall model significance with less than 0.05 value, it means the regression analysis be proceeded. Additionally according to second school of thought the regression sum of square should be greater then residual sum of square for better model fit.4.4.1 CoefficientIf t value is greater then 2 means it is significant. And significance value should be less than 0.05 to make a significant relationship. Here t value is 15.47, showing significant relationship, and sig value is less than 0.000.4.2. DiscussionThis is similar finding with Ryan Vaithianathan, (2009). Which shows that the attitude of consumer is positive towards information provision to patient if asked and similar with the Brekke Kuhn, 2006 study which shows that the doctors rely on the information provided to them through DTCA.I accept the hypothesis that physicians have positive attitude towards DTCA. And it is accepted that the physicians are comfortable in providing information if asked by patents about any DTCAB. According to statistics shown by Data analysis I accept the hypothesis of positive relationship between general attitude of physicians towards DTCA and behavior of physicians if patient asks information has positive relationship and are match with actual prescription generation. Very interestingly it is found that information asking by physician and general attitude are weakly negatively correlated, it can be the area for further research that if more information is asked by patients about any brand may lead to negative attitude of physicians towards DTCA.It is found that through DTCA and patients, it is a way of putting mechanical press on physicians to change their prescribing behavior, (Ry an Vaithianathan, 2009) It was major concern showed by (Morgan, Mintzes barer, 2003) that the regularities authorities should consider DTCA regulations if it has impact on prescribing behavious, and in this study it has shown that the consumer advertising is creating impact in prescription choosen. This study is providing valueable information for pharmaceutical manufacturers and marketers. If more patients would ask for further information of specific drug, it may lead to the actual prescription generation.This study is also a thought provoking study for physicians that in choosing brands they are influenced by patients which may lead to increased cost and unnecessary medicines prescription. This study can be an eye opener for regularity authorities, DTCA is considered as good by physicians but it should be clearly monitored because it also creates pressure on physicians to prescribe certain brands.VI CONCLUSIONPhysicians have positive attitude towards DTCA and consider it suppl ementary in overall health care system. It stimulates patients to visit physician and seek appropriate treatment. Physicians feel comfortable in providing relevant information about DTCAB if asked, and they do not hesitate to prescribe the medicine if it is relevant to disease and patient economic characteristics. 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